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filingDate 2021-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92313aa77fcf019584ff7f0ff35770b4
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publicationDate 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114028343-A
titleOfInvention Brivaracetam quick-release preparation and preparation method thereof
abstract The invention relates to a brivaracetam quick-release preparation and a preparation method thereof, belonging to the field of pharmaceutical preparations. The quick release preparation comprises active ingredient distributexist or salt thereof and auxiliary materials, wherein the viscosity of 1g/100mL of aqueous solution of the quick release preparation is 2-150mpa.s, and the auxiliary materials comprise thickening agents. The preparation method comprises the following steps: pulverizing and sieving the filler for later use; weighing the active ingredients in the prescription amount, premixing the active ingredients with a flavoring agent, a thickening agent and an adhesive, and sieving; transferring the sieved and mixed materials into a fluidized bed, setting the air inlet temperature and the material temperature, granulating by using purified water as a wetting agent, controlling the water content within 3%, sieving, and controlling the fine powder below 80 meshes within 12% for later use; and finally, subpackaging. The brivaracetam quick-release preparation provided by the invention has a good taste masking effect, is not sticky, is convenient for old people, children and other patients with swallowing difficulty or special conditions to take, and can slowly release psychogenic adverse reactions such as sleepiness, dizziness, fatigue and the like.
priorityDate 2021-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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