| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29a7aa981dcfe4b0b8a33e822b062da6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-10104
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-10081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-10088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-10108
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-30008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-20104
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-20076
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-481
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-10064 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4842
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4528
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T7-0014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T7-0012
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H30-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H20-17 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-103
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-06 |
| filingDate |
2020-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee5429fab704649dcc29da51e47dfc7d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93ba83965ed6e4e4a5195f147a8b3ab2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f350ef1b02ffc20089dfcab016fde5a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57887b70f89b0d4583b6b54c7a0d6411
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_026108a610ac05d118917ad4f99a14ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f003a705ee66bf593e1db660f2718478 |
| publicationDate |
2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114025666-A |
| titleOfInvention |
Compositions and methods for assessing macrophage-mediated pathology |
| abstract |
Compositions and methods for assessing the involvement of macrophages in inflammation of one or more joints in a subject are disclosed. In certain aspects, the disclosed methods comprise the steps of: administering to a subject a composition comprising a mannosylated dextran construct having an imaging moiety conjugated thereto; obtaining the subject's first One or more planar images of a joint; define a region of interest (ROI) containing said first joint; define a joint-specific reference region (RR); by evaluating the ratio of the mean pixel intensity of the ROI to the mean pixel intensity of the RR and comparing the MARTAD of the first joint with the normal MARTAD value of the corresponding joint, and wherein macrophage participation is indicated by a joint-specific MARTAD value exceeding a predetermined threshold of the normal MARTAD value. |
| priorityDate |
2019-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |