http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114014893-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e8f724978a0e15cd2e730fa7731c000 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D517-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-002 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D517-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-165 |
filingDate | 2021-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_350d59850a72170addc2bbd455996c7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26dcef70256fd70752d6801590f2a428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e453f2ecc5a65f92295e19b6f5dc68a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9ead85aaea31f6097d10d1c1349273a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d180f21e2148d614d80d40df32948799 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1eaef179bc704d578b91e03661633915 |
publicationDate | 2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114014893-A |
titleOfInvention | Selenium-containing iron group metal complex and preparation method and application thereof |
abstract | The invention discloses a selenium-containing iron group metal complex and a preparation method and application thereof, wherein selenadiazole (PhenSe for short) is mixed with ethylene glycol, and (NH) is added after ultrasonic homogenization 4 ) 2 OsCl 6 Refluxing at high temperature, cooling, adding excessive sodium chlorate, adding water, precipitating solid, centrifuging to remove supernatant to obtain black brown solid as target complex Os (PhenSe) 3 (ClO 4 ) 2 (ii) a Mixing PhenSe with ethanol, ultrasonically stirring to obtain suspension, and adding RuCl 3 ยท3H 2 Mixing O powder in ethanol, adding the suspension, refluxing at high temperature, cooling, standing, and collecting the supernatantOrange yellow, taking the supernatant, recrystallizing, separating out orange yellow crystal, and collecting as target complex Ru (Phense) 3 Cl 2 . By using a ligand as a contrast, the ruthenium and osmium complexes using the carbon diazole as the ligand are synthesized by a similar method. By introducing selenium, the invention obviously enhances the growth inhibition effect of the osmium complex on all malignant breast cancers and also enhances the anti-tumor activity of the ruthenium complex. |
priorityDate | 2021-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 52.