| abstract |
The invention belongs to the technical field of cefditoren pivoxil impurity research, and relates to a preparation method of methoxymethyl cefditoren pivoxil, a preparation method of methoxymethyl cefditoren pivoxil, and the reaction equation This can be represented by the process shown below: Compound cefditoren pivoxil shown in formula II and compound halomethyl methyl ether shown in formula III react to generate compound methoxymethyl cefditoren pivoxil shown in formula I, and the reaction uses sodium iodide as a catalyst, carried out in the presence of an acid binding agent. The invention provides a preparation method of methoxymethyl cefditoren pivoxil, which has simple synthesis steps, mild reaction process, easy operation and high product purity. |