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publicationDate 2022-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114000262-A
titleOfInvention Drug-loaded polydopamine-coated nanofiber dressing and preparation method thereof
abstract The invention belongs to the technical field of wound dressings, and particularly relates to a drug-loaded polydopamine-coated nanofiber dressing and a preparation method thereof. The wound dressing takes polycaprolactone nanofiber as a base material, firstly, polydopamine-coated nanofiber is synthesized, and then, a nanofiber membrane with antibacterial effect, photothermal effect and antioxidant property is prepared through loading of epsilon-polylysine. The wound dressing has simple preparation process and no toxicity. Experiments prove that the drug-loaded polydopamine-coated nanofiber dressing is successfully prepared and has high antioxidant effect. Bacteriostatic experiments prove that the nanofiber dressing has good bacteriostatic ability. Cell experiments prove that the nanofiber dressing is non-toxic. The drug-loaded polydopamine-coated nanofiber dressing is simple to prepare and has a wide application prospect in the field of wound dressings.
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