Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db9efde660b78f98b102046e09d07ab7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-069 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
2021-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7e333283f13a9c552374a926602ae89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8241f479f2d8abea51f307e3becc2fea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75d73eb71e232d24aedbebf882666b10 |
publicationDate |
2022-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-113999877-A |
titleOfInvention |
Gene editing method and application of mesenchymal stem cell medicine |
abstract |
The invention discloses a gene editing method and application of a mesenchymal stem cell medicament. The invention finds that the target gene can be transfected into MSC by using the Cas9+ vascular endothelial cell secretory vesicle, the accurate editing can be efficiently realized by a Crispr-Cas9 gene editing system, the function of the MSC is enhanced, and the characteristics of MSC immunoregulation and growth promotion are retained. |
priorityDate |
2021-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |