http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113999142-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D203-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C61-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D203-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06 |
| filingDate | 2021-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113999142-B |
| titleOfInvention | A kind of preparation method of chiral N-Boc-trans-1,2-cyclohexanediamine |
| abstract | The invention discloses a preparation method of chiral N-Boc-trans-1,2-cyclohexanediamine, belonging to the technical field of organic synthesis. Taking 7-azabicyclo[4.1.0]heptane as raw material and di-tert-butyl dicarbonyl to react under alkaline conditions to generate N-Boc-7-azabicyclo[4.1.0]heptane 2; then react with ammonia water Ring-opening under high temperature and pressure to obtain N-Boc-trans-1,2-cyclohexanediamine 3; use (S)-3-cyclohexene formic acid to form a salt and resolve to obtain N-Boc-(1S,2S )‑1,2‑cyclohexanediamine. The method is easy to operate, the steps are relatively simple, and the resolving agent can be recycled and used mechanically, which has potential industrial scale-up prospects. |
| priorityDate | 2021-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.