http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113995740-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae18c79bf0aac76122b2735592103a56 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-122 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 |
filingDate | 2021-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ba3e64969be1e041b144203b7d8e182 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bbfef64310384bdf6c2ef95d74a7700 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1deb990dd4319d5b96243b10085c277 |
publicationDate | 2022-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113995740-A |
titleOfInvention | Application of shikonin as synergist of carbapenem antibiotics against carbapenem-resistant bacteria |
abstract | The invention discloses the application of shikonin as a synergist of carbapenem antibiotics in resisting carbapenem drug-resistant bacteria. The present invention uses drug sensitivity test and combined drug sensitivity test to screen out the synergist-shikonin of meropenem from 20 kinds of traditional Chinese medicine monomers. Class-resistant bacteria have a good bactericidal effect. In particular, it can produce a synergistic inhibitory effect on Enterobacteriaceae bacteria carrying carbapenem resistance genes bla IMP-4 , bla NDM-1 , bla VIM-1 and/or bla OXA-23 genes. The present invention provides a new technical means for the prevention and control of carbapenem-resistant bacteria. |
priorityDate | 2021-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.