| abstract |
The invention belongs to the technical field of biomedical detection, and discloses a diabetic retinopathy detection biomarker, a detection kit and application, wherein the diabetic retinopathy detection biomarker is miRNA-375-3p, and the marker has The nucleotide sequence is shown in SEQ ID NO:1. The invention determines that the change in the expression level of miRNA-375-3p is significantly correlated with the occurrence of diabetic retinopathy. miRNA‑375‑3p can be used as a biomarker for the early diagnosis of diabetic retinopathy, and the progression and recurrence after treatment of diabetic retinopathy are regularly assessed. The invention provides important reference basis for early diagnosis, prognosis judgment and early intervention treatment of diabetic retinopathy, has great practical clinical value, can intervene and treat early, and reduce unnecessary treatment and cost of non-high-risk recurrence patients . |