http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113980144-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate | 2021-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113980144-B |
| titleOfInvention | A kind of polypeptide analog and its application |
| abstract | The invention discloses a polypeptide analog and an application thereof. The polypeptide in the polypeptide analog is Tat-Sam68, and its amino acid sequence is shown in SEQ ID NO. 3; wherein, Tat is a membrane-penetrating structure sequence of 11 amino acids, Specifically as shown in SEQ ID NO.1; Sam68 is a 15 amino acid fragment on the Sam68 protein sequence with the highest affinity with MD2, as shown in SEQ ID NO.2. The polypeptide analog can be used in the preparation of a drug for intervening and treating frostbite. The polypeptide analogs of the present invention can specifically target MD2 and bind to endogenous MD2, thereby inhibiting MD2-mediated cell damage induced by low temperature, and is expected to improve frostbite. |
| priorityDate | 2021-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.