| abstract |
The invention belongs to the technical field of chemical synthesis, and relates to a method for preparing raw material medicine of acetyl gastrodine, which comprises the following steps: adding 4-hydroxybenzyl alcohol and acetyl bromide-alpha-D glucose into an inorganic alkali aqueous solution/organic solvent two-phase mixed solution containing a phase transfer catalyst, removing a water layer after the reaction is finished, and evaporating under reduced pressure to remove the organic solvent to obtain the acetyl gastrodin product. The invention selects 4-hydroxybenzyl alcohol and acetyl bromide-alpha-D glucose as raw materials, prepares the acetyl gastrodin by one-step reaction, and has simple and convenient process and high yield. |