| abstract |
The invention provides a tegafur derivative and application thereof in preparing an anti-tumor medicament, and the tegafur derivative has a general formula (I). Research on degradation of the tegafur derivative mediated by nitroreductase shows that the tegafur derivative can be well degraded to generate tegafur under the nitroreductase condition, and in-vivo experiments show that the tegafur derivative has better anti-tumor activity and has less toxic and side effects than tegafur and fluorouracil |