abstract |
The invention relates to the technical field of medicinal chemistry synthesis, and proposes a method for synthesizing a viral drug N,N-dimethyl-5-hydroxytryptamine-N 12 -oxide, comprising the following steps: S1, combining N,N -Dimethyl-5-hydroxytryptamine and phase transfer catalyst are added into ethanol and stirred to form a homogeneous solution; S2, dropwise add hydrogen peroxide ethanol solution, control dropwise temperature 0~5 ℃, continue to react after dropwise addition; S3, after deal with. Through the above technical solution, the problems of complex synthesis process, many chemical raw materials used, low yield and high cost in the prior art are solved. |