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filingDate 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf35682470ed39e8d7174aabb28d33ae
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publicationDate 2022-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113979856-A
titleOfInvention Method for recovering tert-butylamine and isooctanoate from potassium clavulanate still residue
abstract The invention belongs to the technical field of pharmacy, and relates to a method for recovering tert-butylamine and isooctanoate from potassium clavulanate raffinate. Set layering to obtain the water phase and isooctanoic acid oil phase containing tert-butyl ammonium sulfate; use alkali to adjust pH to basicity to the water phase containing tert-butyl ammonium sulfate salt, then distill to obtain tert-butylamine; isooctanoic acid oil phase is by adding lye , converted into isooctanoate aqueous solution, purified by ultrafiltration, decolorization and impurity removal with macroporous adsorption resin, and then evaporated, concentrated and crystallized to obtain high-quality isooctanoate. The invention realizes the recovery and reuse of the residual liquid from the kettle, creates a new economic growth point for the enterprise, reduces and avoids the environmental pollution caused by the organic matter, and achieves the strategic goal of safety, environmental protection and win-win for the enterprise.
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