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filingDate 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b41ffd6796c44ecb52496692633f7347
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publicationDate 2022-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113976113-A
titleOfInvention A kind of catalyst for megestrol acetate synthesis, its preparation method and application
abstract The invention discloses a catalyst for the synthesis of megestrol acetate, its preparation method and application. After the activated carbon is stirred in the ammonium oxalate solution, filtered and washed with water, the ammonium oxalate treated activated carbon is obtained; step 3, the ammonium oxalate treated activated carbon is placed in the gallium salt solution and stirred, and filtered to obtain the gallium modified activated carbon; step 4, the gallium modified activated carbon is obtained; The activated carbon is placed in the palladium chloride solution, stirred, and the stirring process controls the pH of the system to be 7 to 9, filtered, and washed to obtain a catalyst precursor; step 5, reduce the catalyst precursor in step 4 to obtain megestrol acetate synthesis. catalyst. The catalyst of the invention has a yield of more than 98.0% in the reaction of synthesizing megestrol acetate from α-hydroxy-6-methylenepregna-4-ene-3,20-dione, and has high reactivity and activity.
priorityDate 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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