| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25202fe4a5c7293a0a5e07026316bf12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7135 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate |
2021-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8c43dd3f2bfb754dedc84f4732b098e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17853beea70cb4668ea05e17c28521af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_758116cb01e83258110311b9516ab6f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c612b14a8aa75ff040561b37788a9afb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_506fc1f045ec3545a862b12a93740f8a |
| publicationDate |
2022-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113952354-A |
| titleOfInvention |
Application of auranofin in the preparation of drugs for demyelinating diseases |
| abstract |
The invention relates to the technical field of biomedicine, in particular to the application of auranofin in the preparation of a drug for the treatment of demyelinating diseases. The present invention proves through in vivo experiments that auranofin has a significant effect of maintaining the integrity of the blood-brain barrier, has a significant inhibitory effect on the infiltration of inflammatory cells, and also has a significant inhibitory effect on demyelination damage, which can significantly alleviate demyelination. The pathogenesis and severity of disease in sheath animals provide new evidence for the treatment of demyelinating diseases and multiple sclerosis. |
| priorityDate |
2021-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |