Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01e8b3ece681b02d7041a6b112d33218 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7155 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20 |
filingDate |
2021-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88c32e890feeeceba6a6323c6da5c522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc73f01038942f0f945396c191fcb100 |
publicationDate |
2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-113943374-A |
titleOfInvention |
A polypeptide complex of interleukin 15 and its receptor |
abstract |
The present invention relates to the field of biomedicine, in particular, to a disulfide bond-engineered polypeptide complex comprising interleukin 15 and its receptor. There is a non-natural interchain bond between the IL15 and IL15Rα, and the non-natural interchain bond is formed between the first mutated residue of IL15 and the second mutated residue of IL15Rα, the first mutated residue of IL15 The E at position 90 was mutated to C, and the second mutated residue of IL15Rα was the P mutation at position 67 C. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023138573-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023046116-A1 |
priorityDate |
2021-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |