http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113943232-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1f67acbbaaeae47294f49c3df96b2e6
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C259-06
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C259-06
filingDate 2021-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f55b85c4857407892eb4376963bd47b
publicationDate 2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113943232-A
titleOfInvention A method for extracting vorinostat from salamander peptides
abstract The invention discloses a method for extracting vorinostat from salamander peptide, comprising the following steps: dissolving salamander peptide in water to obtain an aqueous solution of salamander peptide; adsorbing the salamander peptide aqueous solution to remove the weak polarity in the salamander peptide aqueous solution organic molecule; carry out chromatographic elution on the eluent obtained in step (2) to separate the target substance; elute the substance obtained in step (3) with a mixture of dimethyl sulfoxide and ethanol; step The eluent obtained in (4) removes the water solvent; the material obtained in the step (5) is subjected to recrystallization to obtain white crystals, and the white crystals are vorinostat, and the obtained vorinostat is at -20 ° C Save under. The invention fills in the blank that vorinostat can be extracted from giant salamander peptide in the prior art.
priorityDate 2021-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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