| abstract |
The invention relates to a recombinant human interferon alpha 1b and a preparation method thereof, belonging to the field of biological medicine. The method is simple to operate, can enable escherichia coli to express the human interferon alpha 1b in the periplasm cell space, can capture the human interferon alpha 1b without crushing cells, reduces the release of host protein, simplifies the purification step, and is favorable for the industrial production of the human interferon alpha 1b, and the purity and the activity of the obtained human interferon alpha 1b are high. |