http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113930407-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0dccba7e7d99220454ca04ee8951cde |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-623 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 |
| filingDate | 2021-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73c693fd5065e9bbbdb9e7ff3374220e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb98f743dd8bca4fad7535352cad42bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5b86bc078169836ec83ef2bc4cda876 |
| publicationDate | 2022-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113930407-A |
| titleOfInvention | Hydrolase and application thereof in biocatalytic synthesis of 4 '-methylamino-5' -hydroxy-avermectin |
| abstract | The invention provides a hydrolase and application thereof in biocatalytic synthesis of 4 '-methylamino-5' -hydroxy-avermectin, wherein an amino acid sequence of the hydrolase is selected from SEQ ID NO: 1. SEQ ID NO: 3. SEQ ID NO: 5 and SEQ ID NO: 7, one of which is shown. The hydrolase screened by the invention can replace deprotection reaction in the process of synthesizing emamectin benzoate by a biological catalysis method. 5-O-allyl formate-4 ' -methylamino-abamectin is used as a substrate, and hydrolysis of esterase is utilized to obtain the product 4 ' -methylamino-5 ' -hydroxy-abamectin, so that a complex chemical synthesis process can be avoided, and a new way is provided for synthesizing the product 4 ' -methylamino-5 ' -hydroxy-abamectin by a biological method. |
| priorityDate | 2021-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 164.