http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113930335-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6901 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6849 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M21-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 |
| filingDate | 2021-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113930335-B |
| titleOfInvention | Nano enzyme cascade bioreactor and preparation method and application thereof |
| abstract | The invention discloses a nano enzyme cascade bioreactor (MEGR) and a preparation method and application thereof. The invention provides a nano enzyme cascade bioreactor, which is a compound obtained by connecting a substance A to the surface of a substance B; the substance A is a carbon dot nanoenzyme coupled with a CD63 antibody and a hypoxic inhibitor; the substance B is an exosome. According to the invention, the carbon dot nanoenzyme is modified by utilizing exosome in a bionic manner, so that the enrichment capacity of tumor tissues is improved; natural NADPH oxidase 2 on the surface of the exosome is used for providing more catalytic substrates for the carbon dot nanoenzyme; RSR13 was used to improve tumor tissue hypoxia, providing more oxygen for NADPH oxidase 2. The invention can realize the synergistic linkage and synergism to inhibit the growth of the tumor. |
| priorityDate | 2021-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.