http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113921079-A

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filingDate 2021-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90eb40eeddec12115a3c8ad4b8c04d0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b0f730f7f6b369708ca3619aa2fbaf9
publicationDate 2022-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113921079-A
titleOfInvention Construction method of MSI prediction model based on immune-related genes
abstract The invention relates to a method for constructing an MSI prediction model based on immune-related genes, comprising the following steps: collecting a training set and a verification set for constructing an immune-related MSI prediction model irMSIs from the Cancer Genome Atlas database; selecting immune-related genes from the immunology database, and Differential genes were screened out; according to the screened differential genes, the immune-related MSI prediction model irMSIs was constructed by LASSO logistic regression algorithm; the prognostic risk was verified by using the immune-related MSI prediction model irMSIs. The invention provides the application of immune-related genes in the prediction of MSI status. Combined with immune-related genes, a group of characteristic genes that can stably predict MSI in digestive tract tumors, especially colon cancer, are found, and the prognosis of colon cancer can be well predicted. risk.
priorityDate 2021-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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