http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113912735-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac31afbea1cbbb03498644721ffb4a62 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-68 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate | 2020-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9e393d1768374d5de025626356c39b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ad10eb2bb718135ffd35ddd776cd098 |
publicationDate | 2022-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113912735-A |
titleOfInvention | Polypeptide dimer and use thereof |
abstract | The present invention provides a polypeptide dimer comprising a first polypeptide and a second polypeptide, wherein the first polypeptide comprises a first dimerization domain and a polypeptide of interest, wherein the polypeptide of interest is located at a first end of the first dimerization domain, wherein the second polypeptide comprises a second dimerization domain and a binding domain, wherein the binding domain is located at a first end of the second dimerization domain, wherein the first polypeptide and the second polypeptide form a dimer through the first dimerization domain and the second dimerization domain, and the first end of the first dimerization domain is adjacent to the first end of the second dimerization domain, the binding domain being capable of binding to a site of interest on the polypeptide of interest. The invention also provides nucleic acids and vectors encoding the polypeptide dimers of the invention, host cells comprising the nucleic acids and vectors, and the use of the polypeptide dimers for treating diseases, such as cancer. |
priorityDate | 2020-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 736.