| abstract |
The invention belongs to the technical field of biomedicine, and in particular relates to an angiotensin-converting enzyme 2 inhibitor and its application, and an anti-coronavirus infection drug. Chemical structure, R 1 and R 2 can be selected as hydrogen, halogen, amino, amine, hydroxyl, cyano, alkyl, cycloalkyl, alkoxy, X can be selected as heteroatom such as N, O, S, Y can be selected For alkyl or amido. After testing, the above-mentioned angiotensin-converting enzyme 2 inhibitor has ACE2 inhibitory activity, and can be used as a new type of angiotensin-converting enzyme 2 inhibitor. Potential for infectious agents. (I). |