http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113908265-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97651de1ceeb2411cad2574055776c20 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5254 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10034 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-235 |
| filingDate | 2020-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d5c6154479bc012fe25d6124aedcd4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2196084947be84ce0ddff53447b0c6fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ee786ccda8a1c83752af2a8f53716dc |
| publicationDate | 2022-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113908265-A |
| titleOfInvention | Human type 4 and type 7 adenovirus attenuated live vaccine and application thereof |
| abstract | The invention belongs to the fields of biomedicine and virology, and relates to a human type 4 and type 7 adenovirus attenuated live vaccine and application thereof. The inventor finds out nucleotide regions closely related to virus virulence in human adenovirus type 4 and 7 genomes for the first time, and the modification of the nucleotide regions can greatly reduce the virulence of adenovirus and keep the immunogenicity of the adenovirus. On the basis, the bivalent adenovirus vaccine taking attenuated replication type human adenovirus 4 and 7 as main components is disclosed, has ideal immunogenicity, can induce organisms to efficiently generate binding antibodies and neutralizing antibodies to viruses, and has excellent immune protection. |
| priorityDate | 2020-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.