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filingDate 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be2a3e3cb67298236a3f147984d9bd8d
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publicationDate 2022-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113908134-A
titleOfInvention A kind of preparation method of cefadroxil dispersion-coated tablet
abstract The invention belongs to the technical field of pharmaceutical preparations, and provides a cefadroxil dispersion-coated tablet and a preparation method thereof, which are prepared from the following components in parts by weight: 250 parts of cefadroxil, 185 parts of microcrystalline cellulose, 25 parts of propyl cellulose, 37.5 parts of sodium starch glycolate, 1.25 parts of magnesium stearate, and 174.8 parts of ethanol; the coated tablet is stomach-soluble, and the stomach-soluble film coat is prepared from stomach-soluble coating powder and purified water ; comprising the following steps: S1, weighing each raw material component in proportion; S2, preparation of cefadroxil tablets; S3, preparation of coating liquid; S4, coating. The cefadroxil-coated tablet prepared by the invention adopts a water-soluble coating material, which has the advantages of rapid dissolution and rapid onset of action, and meets the requirements of rapid absorption of antibiotic medication and peak blood drug concentration in a short time. , Because the coating treatment covers the odor, it avoids disintegration in the mouth and causes poor patient compliance and is easy to be taken orally.
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