| abstract |
The invention relates to medicines, in particular to a briracetam medicine solution and a preparation method thereof. A briracetam drug solution, comprising briracetam, a buffer pair and water; the buffer pair is malic acid and sodium malate; or the buffer pair is sodium acetate and glacial acetic acid; when the buffer pair is malic acid When and sodium malate, the weight ratio of malic acid and sodium malate in the described briracetam drug solution is (1-3): (3-1), the weight sum of malic acid, sodium malate and briracetam The weight ratio of racetam is (2-6): (9-11); When described buffer pair is sodium acetate and glacial acetic acid, the weight ratio of sodium acetate, glacial acetic acid in described briracetam drug solution is ( 1-3): (0.009-0.003); and the content of sodium acetate in the briracetam drug solution is 1-2.5mg/mL. The briracetam medicinal solution of the invention can ensure the stability of the briracetam, and also has better solution color stability. |