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filingDate 2021-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1683a82cce18901822f1dde93e69852
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publicationDate 2022-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113892644-A
titleOfInvention A kind of procyanidin nanoparticle complexed and encapsulated by polyelectrolyte and preparation method thereof
abstract The invention discloses a polyelectrolyte complex-encapsulated procyanidin nanoparticle and a preparation method thereof. The preparation method comprises the following steps: adding a chitosan solution with a concentration of 0.015-0.2% (m/v) dropwise to an equal volume of In the procyanidin-chondroitin sulfate mixed solution with concentrations of 0.025-0.075% (m/v) and 0.067-0.5% (m/v) respectively, adjust the pH of the suspension to 2.5-4.5, and continue to stir for 2-3 hours The obtained suspension is subjected to ultrasonic treatment with an ultrasonic time of 0.5-4min and an amplitude of 30-50%, finally obtaining a chitosan/cartilage sulfate encapsulating procyanidin with good particle size between 200-300 nmn and good physical and chemical stability Nanoparticles encapsulation system. The preparation method of the invention is simple, the production cost is low, the prepared nano-particles have good stability, and have a good protective effect on the antioxidant properties of procyanidins.
priorityDate 2021-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 38.