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filingDate 2021-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_265d40a2ba39314881df52f5a897d865
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publicationDate 2021-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113866299-A
titleOfInvention Method for detecting neurotransmitter in dialysate
abstract The invention belongs to the technical field of analytical chemistry, and provides a method for detecting neurotransmitter in dialysate. The invention uses acetonitrile as a mobile phase B, uses ammonium formate aqueous solution as a mobile phase A, adopts a mass spectrum detection mode of simultaneous scanning of positive ions and negative ions, completes simultaneous qualitative and quantitative detection of 13 neurotransmitters of 4 types for the first time, has short analysis time and accurate and reliable qualitative and quantitative detection results, does not need to analyze dialysate to be detected by different detection instruments or different mobile phase conditions, saves the sample amount and the detection time of the sample, provides necessary premise for on-line detection, and has promising clinical application prospect. Before the ultra-performance liquid chromatography-mass spectrometry detection, the method enriches the dialysate to be detected, and realizes the detection of the dialysate with low neurotransmitter content.
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