| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c13f0402219c2a116474be2bfca70c5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8239
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N61-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-865 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H5-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H6-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P1-00 |
| filingDate |
2021-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4322284fb25f13ecca45477fec45674
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_308400a174cc17d9b0b0733e4a181c1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18f231af91581f1aacd6eff61ae2f883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85b9ea02305ad92cad620d2441bcbff4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd44600a2adaba36292e7733210ba735
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67062ba1266d9c8900c5e4724cc31666
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b80417aac9af5527f2eb6ef81008881
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20d05f08bdde651927f5c25c2a08bae1 |
| publicationDate |
2021-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113862295-A |
| titleOfInvention |
Application of an effector of citrus Huanglongbing as a drug target for screening against citrus Huanglongbing |
| abstract |
The invention discloses the application of an effector of citrus Huanglongbing as a drug target for screening anti-citrus Huanglongbing. The invention finds that the P-ring protein of the flagellar matrix of Huanglongbing can cause significant callus deposition as an effector, and its inhibitor can be used for The prevention and control of citrus Huanglongbing has a good application prospect in the field of citrus Huanglongbing. At the same time, the present invention utilizes the characteristics of small genome, simple culture, short life cycle and stable genetic manipulation of Saccharomyces cerevisiae as a model organism for studying the effector of difficult-to-cultivate bacteria CLas. Overexpression of the flagellar basal P-ring protein of the effector fungus H. citrus citrus in yeast disrupted the intrinsic physiology of S. cerevisiae, resulting in changes in the phenotype of S. cerevisiae and inhibiting the proliferation of yeast cells. At the same time, the transient expression in tobacco leaves mediated by Agrobacterium tumefaciens confirmed that it could induce local allergic necrosis and callus deposition and other plant defense responses in tobacco leaves. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114456249-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114478748-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114478751-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114958875-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114958875-B |
| priorityDate |
2021-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |