http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113862218-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29ce560b2cad4652b3d77e980e87699f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2509-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2509-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate | 2021-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca2cf16fb63eb1c441c5c158475f2296 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b5085aa64739b6eab676e20d2338c7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95c844347b40687b11b2db7117233ae3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_808a6cadf8d6902923783d597d72a93a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ed44da0ecdc21fb0ea3479393ab8608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29b8d6f9b65a112d26a92a3e1e6360b4 |
| publicationDate | 2021-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113862218-A |
| titleOfInvention | Tumor-associated perivascular cell subset and preparation method and application thereof |
| abstract | The invention belongs to the technical field of biology, and discloses a tumor-associated perivascular cell subset, a preparation method and application thereof, wherein the tumor-associated perivascular cell subset expresses GJB 2. The invention utilizes the high-dimensional single cell sequencing technology to carry out single cell transcriptome analysis and downstream cell functional verification on a primary focus, a metastasis positive lymph node and a non-metastasis lymph node of a patient with the invasive lung adenocarcinoma, reveals that independent tumor-related perivascular cell subsets exist in a microenvironment of the tumor of the invasive lung adenocarcinoma for the first time, and specifically expresses PDGFRb + GJB2 + CSPG4 ‑ Is'The identity label' is successfully sorted, amplified and preserved by the flow purification of characteristic antibodies and the immunofluorescence identification, and the subpopulation is further verified by cytofunction to obviously promote the invasion capacity of lung cancer cells, has the capability of forming immature and malformed blood vessels, and is an ideal cell tool for researching lung cancer tumor blood vessel abnormal mechanisms and targeting blood vessel normalization drugs in the field. |
| priorityDate | 2021-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.