http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113861518-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2405-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2305-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2389-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2489-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 |
filingDate | 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2023-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2023-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113861518-B |
titleOfInvention | A hyaluronic acid-based thixotropic hydrogel for joint prosthesis lubrication and preparation method thereof |
abstract | The invention discloses a hyaluronic acid-based thixotropic hydrogel used for joint prosthesis lubrication and a preparation method thereof, and relates to the technical field of bionic lubricants. The hyaluronic acid-based thixotropic hydrogel has a volume ratio of 1 ~16:4 neutral cross-linked hyaluronic acid or sodium hyaluronate solution and 4~6wt.% protein solution are prepared, and the cross-linked hyaluronic acid or sodium hyaluronate solution has a volume ratio of 1~10: 500 cross-linking agent and 7-10wt.% hyaluronic acid or sodium hyaluronate alkaline solution cross-linking reaction. The preparation method of the hyaluronic acid-based thixotropic hydrogel provided by the present invention has a simple process and low preparation cost; when the prepared hyaluronic acid-based thixotropic hydrogel is used as a joint prosthesis lubricant, it has good lubricating properties , can effectively reduce the wear and tear of the joint prosthesis and reduce the coefficient of friction, and has excellent biocompatibility at the same time. |
priorityDate | 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.