http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113861278-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20022 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate | 2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113861278-B |
| titleOfInvention | A recombinant novel coronavirus RBD trimeric protein vaccine producing broad-spectrum cross-neutralizing activity, its preparation method and application |
| abstract | The present invention discloses a recombinant RBD trimeric protein that simultaneously produces cross-neutralizing activity against multiple novel coronavirus (SARS-CoV-2) epidemic strains. The trimeric protein is composed of three novel coronavirus S proteins. The subunit composition of the RBD region, the amino acid sequences of the three novel coronavirus RBD regions are the same or at least one is different; when the amino acid sequences of the three novel coronavirus RBD regions are the same, the amino acid sequence is as shown in SEQ ID No. 2 or the amino acid sequence shown in SEQ ID No. 3, or a sequence having more than 95% homology thereto. Using the RBD trimeric protein as the antigen and adjuvant, the immune body can simultaneously produce high-titer neutralizing antibodies against a variety of novel coronavirus epidemic strains, which has a certain broad spectrum and can be used for treatment and/or Or prevent novel coronavirus infection and/or novel coronavirus disease. |
| priorityDate | 2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 428.