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filingDate 2021-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113855853-B
titleOfInvention A kind of degradable zinc-lithium alloy surface coating and preparation method and use thereof
abstract A degradable zinc-lithium alloy surface coating, the base of which is a zinc-lithium alloy binary alloy or a ternary alloy, bonded by dopamine hydrochloride, a layer of copper sulfide nanoparticles with photothermal effect in the middle, and a surface of which is a layer of Heat-sensitive polymer material surface protection layer. The invention uses the insulating effect of the surface polymer material coating and changes the exposed area of the zinc substrate and the concentration of released zinc ions through the melting of the coating at different temperatures, thereby solving the problem that the zinc-lithium alloy is degraded too quickly in the body in the early stage of implantation , The cytotoxicity problem caused by the local accumulation of excessive zinc ions; copper sulfide nanoparticles are used as photothermal coupling agents to achieve photothermal conversion under 808nm infrared light irradiation, so that the surface of the material can promote the osteogenic differentiation of human bone marrow mesenchymal stem cells. temperature, improve the effect of bone regeneration.
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