http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113845530-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4baf61b82705468dd1ff913b8ce785f7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
| filingDate | 2021-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5fe0adffab7566d92d188573e07c443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1364cdc6920a0d06477f498dc9394397 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69444abb7d51aee8743df2ed5f738579 |
| publicationDate | 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113845530-A |
| titleOfInvention | A Facile Michal Addition of 2-phenylbenzimidazo[2,1-b]thiazole |
| abstract | The present invention relates to a convenient Michal addition reaction of 2-phenylbenzimidazole[2,1-b]thiazole. In the method, 2-phenylbenzimidazo[2,1-b]thiazole, 1-pentene-3-ketone, Lewis acid and solvent are added into a reaction vessel, and the reaction is stirred at 40-150° C. for 1-10 hours After the reaction was completed, it was cooled to room temperature, the reaction solution was filtered, and the solvent was evaporated under reduced pressure to obtain a crude product, which was purified by column chromatography to obtain the Michal addition product. The invention relates to a convenient Michal addition reaction of 2-phenylbenzimidazole[2,1-b]thiazole, which has the characteristics of convenient operation, mild conditions, easy availability of raw materials, good functional group tolerance and the like. The Michal addition reaction of sulfur-containing heterocycles such as benzimidazole[2,1-b]thiazole is of great research value. |
| priorityDate | 2021-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.