http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113845458-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2021-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113845458-B |
| titleOfInvention | A kind of fluorescent probe for detecting pyroglutamyl aminopeptidase I, preparation method and application thereof |
| abstract | The invention discloses a fluorescent probe for detecting pyroglutamylaminopeptidase I and a preparation method and application thereof. The method comprises: mixing LXY, HATU and DIPEA, completely dissolving in a dry dichloromethane solution, The reaction was stirred at 0 °C; TPAN solution was added, and the reaction was further stirred at room temperature. After the end, purification was performed to obtain a dark red solid BH1-BOC; BH1-BOC was dissolved in anhydrous dichloromethane, and under ice-salt bath conditions, Add the prepared trifluoroacetic acid solution, and carry out the stirring reaction at room temperature after the dropwise addition; spin dry the solvent, then add dichloromethane to it, repeat several times until all the trifluoroacetic acid is spin dry; purify the crude product to obtain a red solid BH1. |
| priorityDate | 2021-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 218.