http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113842498-B
Outgoing Links
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B33-021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-0015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-047 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01B33-021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01D5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-02 |
filingDate | 2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2023-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2023-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113842498-B |
titleOfInvention | An electrospun membrane scaffold for promoting rotator cuff tendon-bone healing and inhibiting muscle fat infiltration and its preparation method |
abstract | The invention provides an electrospun membrane support for promoting rotator cuff tendon-bone healing and inhibiting muscle fat infiltration and a preparation method thereof. The preparation method of the electrospun membrane scaffold includes the following steps: step 1, ultrasonically dispersing MSNs in ethanol, adding triethoxysilane and stirring, centrifuging to collect nanoparticles, redispersing in sulfuric acid, heating to collect the final product, washing, Freeze-drying to obtain MSN-COOH nanoparticles; step 2, adding lithium salt and MSN-COOH to deionized water, stirring, and then centrifuging to remove the supernatant; the precipitate was dried under vacuum for 40-50h to obtain Li + @MSNs Step 3: Dissolve the polymer material and Li + @MSNs in HFIP, stir to obtain a homogeneous solution, and then use electrospinning technology to prepare an electrospun membrane scaffold with a single fiber in a "cowpea-like" structure. The electrospun membrane scaffold can promote the bone healing of the tendon-bone interface of the rotator cuff and inhibit the fat infiltration of the rotator cuff muscle, and at the same time provide immediate mechanical support after operation, which can provide a new idea for the clinical repair of old rotator cuff injuries. |
priorityDate | 2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 134.