http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113827766-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-402 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0031 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-04 |
filingDate | 2021-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113827766-B |
titleOfInvention | Drug-loaded surgical sealant and preparation method and application thereof |
abstract | The invention provides a drug-loaded surgical sealant, a preparation method and application thereof, and belongs to the technical field of medical adhesives. Wherein the sealant comprises polyethylene glycol activated ester and a medicinal active ingredient for relieving adhesion. The pharmaceutical active ingredient for relieving adhesion comprises indometacin. The surgical sealant further comprises a cross-linking agent; the cross-linking agent is a de novo designed polypeptide chain, specifically CGQADARRWGQICGGVFVGFGPQKHWGCC GC. The invention further realizes the temperature-sensitive and drug-loading characteristics on the basis of preparing the low-swelling hydrogel, thereby further expanding the application field of the hydrogel. Has the advantages of simple and convenient steps, simple operation, easy industrialized mass production and the like, thereby having good value of practical application. |
priorityDate | 2021-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419505305 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID3715 |
Total number of triples: 20.