http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113823353-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c874a91dbf8adf9d08f1b475d203368 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-10 |
| filingDate | 2021-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccf342da51dbaa296ea391f1bd1b3315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86583f49ba2dff7fe10dd45e21bda05f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc187df937d95896f401f6ec91eeb7e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdc9b310d304a8ee5f93969d29b11be4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1217c2d983fb978ad2aaa4aefa5c24e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ab70266e7ac6361a48d8e53d0bf9246 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2329815c1a2e840b00117b76da027987 |
| publicationDate | 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113823353-A |
| titleOfInvention | Gene copy number amplification detection method, device and readable medium |
| abstract | The invention discloses a gene copy number amplification detection method, a device and a readable medium, wherein an amplification negative sample set and an amplification positive sample set are used as training sets, the result of a second independent detection method is used as a standard, the data statistical result of a small panel is used as a characteristic value, an XGB OST model is constructed, and the gene amplification state is predicted. And (3) correcting the copy number of the gene predicted to be amplified, establishing a functional relation between the original copy number of the gene and the result of the second independent detection method by adopting a linear regression method, substituting the original copy number of the amplified gene into the functional relation, and calculating the corrected copy number. The method fully considers the situation of polygene co-amplification and possible experimental deviation, can effectively detect the situation of gene copy number amplification, can obviously reduce the cost and improve the clinical practicability, and effectively improves the detection accuracy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116246694-A |
| priorityDate | 2021-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.