http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113817164-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G73-0206 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G73-0213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G73-0226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G73-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2020-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113817164-B |
| titleOfInvention | A kind of hypoxia-sensitive drug carrier polymer and its preparation method and application |
| abstract | The invention relates to a hypoxia sensitive gene carrier and its preparation method and application. In the invention, polyethyleneimine is grafted with nitro compounds, and then the hypoxia-sensitive gene carrier is formed by a nano-precipitation method. The polyethyleneimine-grafted nitro compound provided by the invention can undergo charge reversal under the joint action of intracellular nitroreductase and NADH, realize gene drug release, and improve transfection efficiency. The invention can load various negatively charged drug molecules, and has broad application prospects and great research value. |
| priorityDate | 2020-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.