| abstract |
The present invention provides nicotine salts, co-crystals, and salt co-crystal complexes, and provides oral products comprising nicotine salts, co-crystals, and/or salt co-crystal complexes. Specifically, the use of nicotine salts of mucic acid, 3,5-dihydroxybenzoic acid and 2,3-dihydroxybenzoic acid with nicotine 4-acetamidobenzoate, nicotine gentisate and Crystalline polymorphic form of nicotine 1-hydroxy-2-naphthoate. The present invention further provides methods for the preparation and characterization of such nicotine salts, co-crystals and salt co-crystals, as well as polymorphic forms thereof. In addition, tobacco products comprising nicotine salts, co-crystals, and/or salt co-crystals, including smoking articles, smokeless tobacco products, and electronic smoking articles, are also provided. |