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filingDate 2020-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4a8f262382f16a81f3d722ce0325112
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publicationDate 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113813271-A
titleOfInvention The application of forsythiaside F in the preparation of anti-coronavirus products
abstract The invention discloses the application of forsythoside F in the preparation of anti-coronavirus products, and belongs to the application in the field of medicine. Molecular docking technology was used to confirm the inhibitory effect of forsythoside F on the S protein and ACE2 protein of the new coronavirus COVID‑19, and the affinity experiment determined that it has a strong affinity with the S protein. Antiviral experiments show that forsythiaside F has a significant inhibitory effect on coronavirus in the range of 1 μM to 100 μM, and the effect is in a dose-effect relationship with the dose. Forsythiaside F is a specific inhibitor of coronavirus with specific novelty, and it can be used to prepare products for the treatment of coronavirus, which has a wide range of practicability.
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