http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113813264-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b9ed41ec71e1e3d004841f54c9eabd8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
| filingDate | 2020-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3534466746d11ace074dac989f48811b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_898b3a267cfa0c17fcafe877055c833b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4a8f262382f16a81f3d722ce0325112 |
| publicationDate | 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113813264-A |
| titleOfInvention | The application of triptolide in the preparation of anti-coronavirus products |
| abstract | The invention discloses the application of triptolide in the preparation of anti-coronavirus products, and belongs to the application in the field of medicine. Molecular docking technology was used to confirm the inhibitory effect of triptolide on the S protein and ACE2 protein of the new coronavirus COVID-19, and the affinity experiment determined that it has a strong affinity with the S protein, and the triptolide was in the range of 5μM to 40μM It has a significant inhibitory effect on coronavirus in the intrinsic cell experiment in a concentration-dependent manner. Triptolide is a coronavirus-specific inhibitor with specific novelty. Triptolide can be used in the preparation of products for inhibiting coronaviruses and has a wide range of practicability. |
| priorityDate | 2020-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.