http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113802188-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B50-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06 |
| filingDate | 2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113802188-B |
| titleOfInvention | Method for immobilizing nucleic acid on the surface of a solid-phase substrate and method for separating substances from a liquid-phase composition |
| abstract | The present invention relates to the technical field of biological detection, in particular, to a method for immobilizing nucleic acid on the surface of a solid phase substrate and a method for separating substances from a liquid phase composition. The method comprises: a) attaching a solution containing nucleic acid to be immobilized on the surface of the solid phase substrate; b) irradiating the surface of the solid phase substrate so that the nucleic acid to be immobilized and the surface of the solid phase substrate are irradiated Photocrosslinking occurs; wherein, the solution contains 3M-4M guanidine isothiocyanate. A high concentration of guanidine isothiocyanate can facilitate the dispersion of nucleic acid molecules more uniformly during the photocrosslinking process, thereby effectively improving the biological activity of the immobilized nucleic acid. |
| priorityDate | 2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 122.