http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113801187-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f90c1df3857ee72900e0015c75caecd9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 |
| filingDate | 2020-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_653dae86492498a38efe77979cde5dca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e72c65a629c930b507262fc595c7d72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18e22caeebc573f53a7abc01758ffbc7 |
| publicationDate | 2021-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113801187-A |
| titleOfInvention | Preparation and application of Michael acceptor type main protease inhibitor targeting novel coronavirus |
| abstract | The present invention relates to a novel class of dual-activated Michael receptor-based novel coronavirus (SARS-CoV-2) primary protease inhibitors, which compounds effectively inhibit or block the replication of SARS-CoV-2. The invention relates to discovery and application of a compound containing a structural general formula, various optical isomers, pharmaceutically active metabolites, pharmaceutically acceptable salts, solvates and prodrugs thereof in preparation of antiviral drugs for treating novel coronavirus pneumonia (COVID-19). The invention also relates to intermediates and synthetic methods for preparing the compounds of the general structural formula. The variables in the structure are defined in the specification, and the compound has a structural general formula as follows: |
| priorityDate | 2020-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 293.