http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113801133-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-20 |
filingDate | 2021-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113801133-B |
titleOfInvention | A kind of ginkgolide and preparation method of monomer contained therein |
abstract | The invention discloses a preparation method of ginkgolide and the monomers contained in it. The eluate of ginkgo leaf extract is obtained according to the preparation method of "Chinese Pharmacopoeia", the eluate of ginkgo leaf extract is concentrated on a column, and the Elution with different concentrations of ethanol, collect ethanol eluents of different concentrations, and treat them respectively to obtain a certain ethanol concentration crystal solution, and crystallize at low temperature to obtain a crude ginkgolide; the crude ginkgolide is recrystallized in an aqueous ethanol solution to obtain a ginkgo with a content of more than 99%. The lactone is composed of ginkgolide A, ginkgolide B, and ginkgolide C; using the differences in the dissolution of each component of ginkgolide in ethanol with different concentrations, ginkgolide A, ginkgolide A, ginkgolide, and ginkgolide with a content of more than 99.5% are obtained respectively. Ginkgolide B, Ginkgolide C monomer. The method of the invention only involves one kind of solvent ethanol, the operation is simple, the product purity is high, and the method is suitable for industrial production. |
priorityDate | 2021-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.