http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113797174-A

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filingDate 2021-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c810624ed69a68615d13455e2890d73
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publicationDate 2021-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113797174-A
titleOfInvention A kind of microgel material and preparation method thereof and application as drug carrier for drug rehabilitation
abstract The invention discloses a microgel material and a preparation method thereof and application as a drug detoxification drug carrier. The microgel material takes PMMA microspheres as the core and P(MEO 2 MA-co-MEO 5 MA) as the shell. PMMA/P(MEO 2 MA‑co‑MEO 5 MA) core-shell smart microgels. The microgel material can be used as a drug detoxification drug carrier to form a drug-loaded microgel for drug detoxification with a temperature-sensitive responsive drug release, which can intelligently release the drug detoxification drug according to changes in body temperature. The invention combines PMMA and P(MEO 2 MA-co-MEO 5 MA) to form a core-shell intelligent microgel, the synthesis conditions are simple, the operation is quick and convenient, and the size and shell thickness can be regulated; The combination of force and force can achieve higher drug loading; P(MEO 2 MA‑co‑MEO 5 MA) can swell or shrink according to the external temperature, and release the drug in a thermosensitive response to changes in body temperature, which can effectively control the dosage, Reduce drug side effects.
priorityDate 2021-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 41.