http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113785797-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bc3b006f5cc41336a2786bb505de102 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate | 2021-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0725d7689a68ad65c7504393de350464 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ee79bafd89806f141a7201452fdcb19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e416f0dc83e553060311e0f51bf248cf |
| publicationDate | 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113785797-A |
| titleOfInvention | Construction method of H3K9 methylase inhibitor inhibition diffuse large B lymphoma cell proliferation model |
| abstract | The invention relates to a construction method of a model for inhibiting proliferation of diffuse large B lymphoma cells by using an H3K9 methylase inhibitor, wherein the H3K9 methylase inhibitor is added into the cultured lymphoma cells, gentian violet is used for staining, and the cell counting observation effect is achieved. (2) Lymphoma cells after H3K9 methylase inhibitor treatment in step 1) were injected subcutaneously in mice and tumor size was observed after 24 days. (3) Detecting the tumor related genes in the tumor tissue in the step 2) by RT-qPCR, and verifying the establishment of a lymphoma cell proliferation inhibition model by the H3K9me2 methylase inhibitor. The verification result is reasonable and accurate, and the experimental process is strict and careful. The invention has simple operation and accurate result, and is favorable for guiding the application of the H3K9me2 methylase inhibitor in the treatment of lymphoma. |
| priorityDate | 2021-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.