| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25202fe4a5c7293a0a5e07026316bf12 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate |
2021-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_065fc8609dfe6df4f8052d50e8932ab7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eacdfa87fce7ab3a592de04c2d3074ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3db6ce38e690e115b24af2139c358e19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ae28fe310404b3e9b97f0e1ec726b6e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3bd2cdcac4b6eeb4e64a3ed1bcee7b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8656519f54af5f4f41a18d684d3c7e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d0d7a0d6593fb7eb665ec9ee8816f65 |
| publicationDate |
2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113750219-A |
| titleOfInvention |
Application of TMEM184C in the preparation of drugs for preventing or treating Japanese encephalitis virus infection |
| abstract |
The present invention relates to the technical field of biomedicine, in particular to a new target of anti-Japanese encephalitis virus (JEV) infection: transmembrane protein 184C (Transmembrane Protein 184C, TMEM184C), and preparation thereof for preventing or treating Japanese encephalitis Application of Viral Infection Drugs. The present invention takes human neuroblastoma SH-SY5Y as the target cell, and uses transcriptome sequencing technology to analyze the effect of dihydroartemisinin on the gene expression of JEV-infected target cells. It plays an important role in SHSY5Y and up-regulates the expression of TMEM184C, which can significantly inhibit JEV infection. The invention provides a new target and a therapeutic scheme for clinical prevention and treatment of the incapacitation of the nervous system caused by Japanese encephalitis virus infection. |
| priorityDate |
2021-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |