abstract |
Disclosed herein are methods for treating cancer by administering to a subject a therapeutically effective amount of RAD1901, or a solvate (eg, hydrate) or salt thereof, and one or more second therapeutic agents (eg, everolimus) Combinations of these drugs provide additional benefit against advanced cancers and/or cancers that are resistant to previous treatments. The cancer is an estrogen-dependent cancer, such as breast cancer, ovarian cancer, colon cancer, endometrial cancer, or prostate cancer. |